This Week in Arthritis Natural Remedy News – February 11, 2013

by admin

Following are news snippets, articles and web posts on news and research about the latest breakthroughs and research on arthritis remedies and cures for your help.

 

USA Today – FDA panel opposes pure hydrocodone painkiller

Experts voted against Zohydro for moderate to severe chronic pain

WASHINGTON (AP) — Government health experts overwhelmingly voted against a stronger version of hydrocodone on Friday, questioning the need for a new form of one of most widely abused prescription painkillers.

The Food and Drug Administration’s panel of pain specialists voted 11-2 with one abstention against Zohydro for moderate to severe chronic pain. The drug was developed as a long-acting pain reliever by San Diego-based Zogenix Inc.

The FDA is not required to follow the group’s recommendation, though it often does so.FDA

The panelists acknowledged that the pill would likely reduce pain, but worried it would exacerbate the national epidemic of prescription painkiller abuse.

“I think the sponsor fulfilled the expectations of FDA, however I think the entire class is problematic in terms of abuse and safety issues,” said professor James Ware of the Harvard School of Public Health.

If approved, Zohydro would be the first pure hydrocodone medication available in the U.S. Currently available products combine the drug with lower-grade painkillers such as acetaminophen.

Hydrocodone is prescribed to treat pain from injuries, surgery, arthritis, migraines and a variety of other ailments.

Hydrocodone-containing pills consistently rank as the first or second most-abused medicines in the U.S., according to the Drug Enforcement Administration.

The drug belongs to a family of medicines known as opiates or opioids because they are chemically similar to… [Read More]

 

New York Times – Study Finds How Genes That Cause Illness Work

By GINA KOLATA

It has been one of the toughest problems in genetics. How do investigators figure out not just what genes are involved in causing a disease, but what turns those genes on or off? What makes one persDrew Angerer-The New York Timeson with the genes get the disease and another not?

Now, in a pathbreaking paper, researchers at the Johns Hopkins University School of Medicine and the Karolinska Institute in Sweden report a way to evaluate one gene-regulation system: chemical tags that tell genes to be active or not. Their test case was of patients with rheumatoid arthritis, a crippling autoimmune disease that affects 1.5 million Americans.

It was an investigation of epigenetics, a popular area of molecular biology that looks for modifications of genes that can help determine disease risk.

“This is one of the first studies that looks for an epigenetic disease association in a really rigorous fashion,” said Dr. Bradley Bernstein of Harvard, who was not associated… [Read More]

 

BBC – Sunshine may ‘Reduce Arthritis Risk’

Living in a sunnier climate may reduce the risk of developing rheumatoid arthritis, according to US researchers.

Their study of more than 200,000 women, published in the journal Annals of the Rheumatic Diseases, suggested a link between sunlight and the risk of developing the disease.

They speculated that vitamin D, which is produced in sunlight, may protect the body.Does  sunshine prevent rheumatoid arthritis?

Experts warned that people should not spend all day in the sun.

Rheumatoid arthritis is caused by the body’s own immune system attacking the joints and it can be intensely painful.

It is more common in women, but the reason why a patient’s own defences turn against them is unknown.

Researchers at Harvard Medical School followed two groups of more than 100,000 women. The first were monitored from 1976 onwards, the second from 1989.

Their health was then compared with estimates of the levels of UV-B radiation they were exposed to, based on where they lived.

In the 1976 group, those in the sunniest parts of the US getting the highest levels of sunshine were 21% less likely to develop rheumatoid arthritis than those getting the least UV radiation.

However, UV levels had no affect upon… [Read More]

 

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